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Article

Effect of the chemokine receptor CCR5 in the development of American cutaneous leishmaniasis in a Southern Brazilian population.

Molecular medicine reports - 1 Jul 2013

Ribas Adriana Danmvolf, Ribas Rejane Cristina, Da Silva Júnior Waldir Veríssimo, Aristides Sandra Mara Alessi, Lonardoni Maria Valdrinez Campana, Watanabe Maria Angélica Ehara, Borelli Sueli Donizete, Silveira Thaís Gomes Verzignassi

Abstract excerpt

American cutaneous leishmaniasis (ACL) shows a wide spectrum of clinical and immunopathological manifestations. The CCR5 chemokine receptor directs the immune response to a Th1 pattern and the mutant allele of this genotype (Δ32/Δ32) results in a less effective response, thus leading to a milder inflammation. The objective of the present study was to investigate the effect of the CCR5 chemokine receptor in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23632983
DOI: 10.3892/mmr.2013.1452

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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