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Article

Amylin and hypertension: association of an amylin -G132A gene mutation and hypertension in humans and amylin-induced endothelium dysfunction in rats.

The Journal of clinical endocrinology and metabolism - 1 Apr 2007

Novials Anna, Rodriguez-Mañas Leocadio, Chico Ana, El Assar Mariam, Casas Sílvia, Gomis Ramon

Abstract excerpt

CONTEXT: Amylin has been linked to the development of hypertension in several pathological states related to hypertension and insulin resistance, although there is scant data regarding its potential mechanisms of action. The -132 G/A mutation located within an activator domain of the amylin gene's promoter was first identified in a small cohort of Spanish patients with type 2 diabetes. OBJECTIVE: The objective of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17213278
DOI: 10.1210/jc.2006-1980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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