Article
Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance.
American journal of hypertension - 1 Sept 2006
Mager Ursula, Kolehmainen Marjukka, Lindström Jaana, Eriksson Johan G, Valle Timo T, Hämäläinen Helena, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Tuomilehto Jaakko O, Pulkkinen Leena, Uusitupa Matti I
Abstract excerpt
BACKGROUND: Ghrelin is a gut-brain hormone, which stimulates food intake and controls energy balance. Recently, it has been shown that ghrelin may also play a role in the regulation of blood pressure (BP) by acting at the sympathetic nervous system. In the present study we genotyped six variants of the ghrelin gene and its promoter, and tested whether these single nucleotide polymorphisms (SNPs) were associated...
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