Article
Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori.
Diabetologia - 1 Apr 2003
Poa N R, Cooper G J S, Edgar P F
Abstract excerpt
AIMS/HYPOTHESIS: Amylin gene mutations are known to predispose Chinese and Japanese subjects, but not Caucasian subjects, to Type 2 diabetes. New Zealand Maori, who have a high prevalence of Type 2 diabetes, have genetic origins in South East Asia. Amylin gene mutations could therefore predispose New Zealand Maori to Type 2 diabetes. METHODS: The amylin gene was screened for mutations in the proximal promoter...
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