Article
Circulating amylin in human essential hypertension: heritability and early increase in individuals at genetic risk.
Journal of hypertension - 1 Nov 2000
Kailasam M T, Parmer R J, Tyrell E A, Henry R R, O'Connor D T
Abstract excerpt
BACKGROUND: Human essential hypertension is a complex trait with poorly understood genetic determination. Insulin resistance is frequently associated with this trait. OBJECTIVE: To determine whether a potentially pathogenic feature of the insulin-resistant state, circulating amylin (islet amyloid polypeptide, co-released with insulin from pancreatic islet beta-cells), is already increased in prehypertensive...
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