Article
Large-scale mapping of mutations affecting zebrafish development.
BMC genomics - 9 Jan 2007
Geisler Robert, Rauch Gerd-Jörg, Geiger-Rudolph Silke, Albrecht Andrea, van Bebber Frauke, Berger Andrea, Busch-Nentwich Elisabeth, Dahm Ralf, Dekens Marcus P S, Dooley Christopher, Elli Alexandra F, Gehring Ines, Geiger Horst, Geisler Maria, Glaser Stefanie, Holley Scott, Huber Matthias, Kerr Andy, Kirn Anette, Knirsch Martina, Konantz Martina, Küchler Axel M, Maderspacher Florian, Neuhauss Stephan C, Nicolson Teresa, Ober Elke A, Praeg Elke, Ray Russell, Rentzsch Brit, Rick Jens M, Rief Eva, Schauerte Heike E, Schepp Carsten P, Schönberger Ulrike, Schonthaler Helia B, Seiler Christoph, Sidi Samuel, Söllner Christian, Wehner Anja, Weiler Christian, Nüsslein-Volhard Christiane
Abstract excerpt
BACKGROUND: Large-scale mutagenesis screens in the zebrafish employing the mutagen ENU have isolated several hundred mutant loci that represent putative developmental control genes. In order to realize the potential of such screens, systematic genetic mapping of the mutations is necessary. Here we report on a large-scale effort to map the mutations generated in mutagenesis screening at the Max Planck Institute...
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