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Article

A new vaccine escape mutant of hepatitis B virus causes occult infection

1 Feb 2015

Abstract excerpt

There is growing public concern regarding assay sensitivity to HBsAg mutants in clinical diagnosis and vaccine escape. The aim of this study is to introduce a new HBsAg mutant strain. The serum samples were those of patient X at the age of 3 months and 3 years respectively, and of her mother immediately before parturition, which were used to amplify the HBsAg-coding DNA fragments by PCR. The HBsAg DNA sequences...

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PMID: 25692622
DOI: 10.4161/21645515.2014.994461

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