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Article

MLC1 polymorphisms are specifically associated with periodic catatonia, a subgroup of chronic schizophrenia.

Biological psychiatry - 15 May 2007

Selch Sandra, Strobel Alexander, Haderlein Julia, Meyer Jobst, Jacob Christian P, Schmitt Angelika, Lesch Klaus-Peter, Reif Andreas

Abstract excerpt

BACKGROUND: The MLC1, located on chromosome 22q13.33, has been suggested as a risk gene for schizophrenia, especially the periodic catatonia subtype. An initially identified missense mutation was found to be extremely rare in other patient cohorts; however, a recent report again argued for an association of two intronic MLC1 single nucleotide polymorphisms (SNPs) with schizophrenia and bipolar disorder. METHODS:...

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Source

Identifiers

PMID: 17210142
DOI: 10.1016/j.biopsych.2006.08.030

Genes

MLC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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