Article
MLC1 gene is associated with schizophrenia and bipolar disorder in Southern India.
Biological psychiatry - 1 Jul 2005
Verma Ranjana, Mukerji Mitali, Grover Deepak, B-Rao Chandrika, Das Swapan Kumar, Kubendran Shobana, Jain Sanjeev, Brahmachari Samir K
Abstract excerpt
BACKGROUND: Chromosome 22q13 has shown linkage with schizophrenia (SCZ) and bipolar affective disorder (BPAD). A missense mutation in MLC1 (putative cation-channel gene on 22q13) co-segregating with periodic catatonic schizophrenia has been reported. We have investigated the relationship of MLC1 with SCZ and BPAD in Southern India. METHODS: All exons and flanking intronic sequences of MLC1 were screened for novel...
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