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Article

Cloning, expression, and characterization of an alternatively spliced variant of human heparanase.

Biochemical and biophysical research communications - 2 Mar 2007

Nasser Nicola J, Avivi Aaron, Shushy Moran, Vlodavsky Israel, Nevo Eviatar

Abstract excerpt

Heparanase is an endoglycosidase that cleaves heparan sulfate in the extracellular matrix (ECM) and hence participates in ECM degradation and remodeling. Heparanase is involved in fundamental biological processes such as cancer metastasis, angiogenesis, and inflammation. Alternative splicing in the coding region of human heparanase was not reported. Here, we report the cloning of a splice variant of human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17208203
DOI: 10.1016/j.bbrc.2006.12.189
PMCID: PMC1852469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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