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Article

Aggregate-centered redistribution of proteins by mutant huntingtin.

Biochemical and biophysical research communications - 2 Mar 2007

Swayne Leigh Anne, Braun Janice E A

Abstract excerpt

Huntingtin is a widely expressed 350-kDa cytosolic multidomain of unknown function. Aberrant expansion of the polyglutamine tract located in the N-terminal region of huntingtin results in Huntington's disease. The presence of insoluble huntingtin inclusions in the brains of patients is one of the...

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Identifiers

PMID: 17208201
DOI: 10.1016/j.bbrc.2006.12.129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17208201-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Aggregate-centered redistribution of proteins by mutant huntingtin.PMID 17208201Read ↗

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