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Article

Development of a rat parathyroid hormone 2 receptor antagonist.

Peptides - 1 Apr 2007

Kuo Jonathan, Usdin Ted B

Abstract excerpt

The parathyroid hormone 2 (PTH2) receptor is a Family B G-protein coupled receptor most highly expressed within the brain. Current evidence suggests that tuberoinfundibular peptide of 39 residues (TIP39) is the PTH2 receptor's endogenous ligand. To facilitate investigation of the physiological function of the PTH2 receptor/TIP39 system, we have developed a novel PTH2 receptor antagonist, by changing several...

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Source

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Identifiers

PMID: 17207559
DOI: 10.1016/j.peptides.2006.12.002
PMCID: PMC1894913

Genes

PTH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Development of a rat parathyroid hormone 2 receptor antagonist.PMID 17207559Read ↗

The Parathyroid Hormone 2 (PTH2) ReceptorSemantic proximity Read ↗

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Tuberoinfundibular peptide 39 binds to the parathyroid hormone (PTH)/PTH-related peptide receptor, but functions as an antagonist.Semantic proximity Read ↗

Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2Semantic proximity Read ↗

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Agonist-specific regulation of parathyroid hormone (PTH) receptor type 2 activity: structural and functional analysis of PTH- and tuberoinfundibular peptide (TIP) 39-stimulated desensitization and internalization.Semantic proximity Read ↗

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