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Article

Identification and Characterization of Two Parathyroid Hormone-Like Molecules in Zebrafish

23 Dec 2003

Abstract excerpt

Zebrafish (Danio rerio) have receptors homologous to the human PTH (hPTH)/PTHrP receptor (PTH1R) and PTH-2 receptor (PTH2R) and an additional receptor (PTH3R) with high homology to the PTH1R. To find natural ligands for zPTH1R and zPTH3R, we searched the zebrafish genomic database and discovered two distinct regions that, when translated (zPTH1 and zPTH2), showed high homology to hPTH. Isolation of cDNAs and...

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Identifiers

PMID: 14684608
DOI: 10.1210/en.2003-0964

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