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[Meiotic and parental origin of extra chromosome 21 in children with regular trisomy 21].

Revista medica del Instituto Mexicano del Seguro Social - 1 Jan 2000

Valle Yeminia, Hernández Guillermo, Barajas-Barajas Leticia Oralia, Vázquez-Herrera José Andrés, Ortiz Rocío, Padilla-Gutiérrez Jorge Ramón, Quintero-Ramos Antonio, Rodarte Katya, Olivares Norma, Rivas Fernando

Abstract excerpt

INTRODUCTION: Down syndrome (DS) or trisomy 21 is the most common chromosomal abnormality in live birth children. Most cases are regular trisomies 21 secondary to a maternal non-disjunction (ND). Meiotic and parental origins have been recently investigated by segregating genetic markers from DNA hypervariable regions. OBJECTIVE: To identify the meiotic and parental origin in children with regular trisomy 21....

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PMID: 17207407

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