Article
Lack of association between the microsatellite polymorphism in intron 2 of human Toll-like receptor 2 gene and bronchiectasis among Koreans.
Respirology (Carlton, Vic.) - 1 Jan 2007
Kim Hee Joung, Lee Hye Won, Lee Ji Eun, Joh Joon Sung, Han Sung Koo, Shim Young-Soo, Yim Jae-Joon
Abstract excerpt
BACKGROUND AND OBJECTIVE: The genetic factors for the development of bronchiectasis are not well understood in most patients. The aim of this study was to elucidate the possible association between bronchiectasis and guanine-thymine (GT) repeat polymorphism in intron 2 of the human Toll-like receptor 2 (TLR2), which has a crucial role in adaptive as well as innate immunity. METHODS: A total of 194 patients with...
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