Article
The prevalence of genetic and serologic markers in an unselected European population-based cohort of IBD patients.
Inflammatory bowel diseases - 1 Jan 2007
Riis Lene, Vind Ida, Vermeire Severine, Wolters Frank, Katsanos Kostas, Politi Patrizia, Freitas João, Mouzas Ioannis A, O'Morain Colm, Ruiz-Ochoa Victor, Odes Selwyn, Binder Vibeke, Munkholm Pia, Moum Bjørn, Stockbrügger Reinhold, Langholz Ebbe
Abstract excerpt
BACKGROUND AND AIM: The aetiology of inflammatory bowel disease (IBD) is unknown, but it has become evident that genetic factors are involved in disease susceptibility. Studies have suggested a north-south gradient in the incidence of IBD, raising the question whether this difference is caused by genetic heterogeneity. We aimed to investigate the prevalence of polymorphisms in CARD15 and TLR4 and occurrence of...
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