Multidrug resistance gene-1 polymorphisms and resistance to cyclosporine A in patients with steroid resistant ulcerative colitis.

doi:10.1002/ibd.20046

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Article

Multidrug resistance gene-1 polymorphisms and resistance to cyclosporine A in patients with steroid resistant ulcerative colitis.

Inflammatory bowel diseases - 1 Jan 2007

Daniel Fady, Loriot Marie-Anne, Seksik Philippe, Cosnes Jacques, Gornet Jean-Marc, Lémann Marc, Fein Francine, Vernier-Massouille Gwenola, De Vos Martine, Boureille Arnaud, Treton Xavier, Flourié Bernard, Roblin Xavier, Louis Edouard, Zerbib Frank, Beaune Philippe, Marteau Philippe

Abstract excerpt

BACKGROUND: Cyclosporine A (CsA) is inconstantly effective in inducing remission in acute attacks of ulcerative colitis (UC) not responding to steroids. This study aimed to establish whether multidrug resistance gene (MDR)1 polymorphisms would be associated with CsA failure. PATIENTS AND METHODS: The distribution of the different genotypes of single nucleotide polymorphisms (SNP) G2677T/A and C3435T of MDR1 exons...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17206635
DOI: 10.1002/ibd.20046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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