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Article

Association of the Catechol-O-Methyl Transferase Gene Val158Met Polymorphism With Blood Pressure and Prevalence of Hypertension: Interaction With Dietary Energy Intake

21 Jul 2011

Abstract excerpt

BACKGROUND: Previous studies of a functional variant of the catechol-O-methyl transferase (COMT) gene, Val158Met, have provided inconsistent results with regard to blood pressure or hypertension. We examined the effect of this variant, the considering environmental factors of daily salt and energy intakes. METHODS: A total of 735 Japanese men (mean age, 47 years) were recruited from two separate occupational...

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PMID: 21776034
DOI: 10.1038/ajh.2011.93

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