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Article

Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2007

Knapp Sylvia, Matt Ulrich, Leitinger Norbert, van der Poll Tom

Abstract excerpt

Oxidized phospholipids that are generated during inflammation exert anti-inflammatory properties and prevent death during murine endotoxemia. Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) inhibits the interaction of LPS with LPS-binding protein and CD14. In this study, we determined the functional properties of OxPAPC and potential interference with CD14 during abdominal sepsis...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17202362
DOI: 10.4049/jimmunol.178.2.993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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