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Article

Regulation of NKG2D ligand gene expression.

Human immunology - 1 Mar 2006

Eagle Robert A, Traherne James A, Ashiru Omodele, Wills Mark R, Trowsdale John

Abstract excerpt

The activating immunoreceptor NKG2D has seven known host ligands encoded by the MHC class I chain-related MIC and ULBP/RAET genes. Why there is such diversity of NKG2D ligands is not known but one hypothesis is that they are differentially expressed in different tissues in response to different stresses. To explore this, we compared expression patterns and promoters of NKG2D ligand genes. ULBP/RAET genes were...

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Share to Receptors, Immunologic
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Share to NK Cell Lectin-Like Receptor Subfamily K

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytomegalovirus Infections

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Share to Histocompatibility Antigens Class I

Share to Receptors, Natural Killer Cell

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 16698438
DOI: 10.1016/j.humimm.2006.02.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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