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Article

Mutational analysis of Escherichia coli MoeA: two functional activities map to the active site cleft.

Biochemistry - 9 Jan 2007

Nichols Jason D, Xiang Song, Schindelin Hermann, Rajagopalan K V

Abstract excerpt

The molybdenum cofactor is ubiquitous in nature, and the pathway for Moco biosynthesis is conserved in all three domains of life. Recent work has helped to illuminate one of the most enigmatic steps in Moco biosynthesis, ligation of metal to molybdopterin (the organic component of the cofactor) to form the active cofactor. In Escherichia coli, the MoeA protein mediates ligation of Mo to molybdopterin while the...

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Identifiers

PMID: 17198377
DOI: 10.1021/bi061551q
PMCID: PMC1868504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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