Article
Genetic characterization of the Neurospora crassa molybdenum cofactor biosynthesis.
Fungal genetics and biology : FG & B - 1 May 2014
Probst Corinna, Ringel Phillip, Boysen Verena, Wirsing Lisette, Alexander Mariko Matsuda, Mendel Ralf R, Kruse Tobias
Abstract excerpt
Molybdenum (Mo) is a trace element that is essential for important cellular processes. To gain biological activity, Mo must be complexed in the molybdenum cofactor (Moco), a pterin derivative of low molecular weight. Moco synthesis is a multi-step pathway that involves a variable number of genes in eukaryotes, which are assigned to four steps of eukaryotic Moco biosynthesis. Moco biosynthesis mutants lack any...
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