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Article

Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations.

The American journal of surgical pathology - 1 Jan 2007

Agaimy Abbas, Wünsch Peter H, Hofstaedter Ferdinand, Blaszyk Hagen, Rümmele Petra, Gaumann Andreas, Dietmaier Wolfgang, Hartmann Arndt

Abstract excerpt

Multifocal hyperplasia of interstitial cells of Cajal (ICC hyperplasia) is a precursor of hereditary gastrointestinal stromal tumors (GISTs) in patients with germline mutations of c-KIT or PDGFRA, but precursor lesions of sporadic GISTs have not been defined yet. Small hyalinizing stromal tumors of the proximal stomach (referred to in this study as GIST tumorlets) were collected prospectively from 98 consecutive...

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Source

Identifiers

PMID: 17197927
DOI: 10.1097/01.pas.0000213307.05811.f0

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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