Article
Frequency, phenotype, and genotype of minute gastrointestinal stromal tumors in the stomach: an autopsy study.
Human pathology - 1 Dec 2011
Muenst Simone, Thies Svenja, Went Philip, Tornillo Luigi, Bihl Michel P, Dirnhofer Stephan
Abstract excerpt
Gastrointestinal stromal tumors are the most common mesenchymal tumors of the human digestive tract. Up to 85% of these tumors show somatic gain-of-function mutation of the receptor tyrosine kinase c-KIT gene. A recent study has shown a high frequency (22.5%) of minute gastrointestinal stromal tumors in stomachs examined during routine autopsies. The aims of our study were to confirm the previously reported...
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