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Article

Activating KRAS and GNAS mutations in heterotopic submucosal glands of the stomach.

Journal of gastroenterology - 1 May 2022

Cho Hourin, Hashimoto Taiki, Naka Tomoaki, Yatabe Yasushi, Oda Ichiro, Saito Yutaka, Yoshikawa Takaki, Sekine Shigeki

Abstract excerpt

BACKGROUND: The heterotopic submucosal gland (HSG) is a common incidental finding in gastrectomy specimens. The majority of HSGs are small incidental lesions, which are also known as gastritis cystica profunda. However, larger lesions may appear as an inverted growth of well-organized mucosa referred to as gastric inverted polyps. METHODS: To determine whether genetic alterations are involved in HSG development,...

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PMID: 35188590
DOI: 10.1007/s00535-022-01863-x

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