Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review.

Abstract excerpt

Gastrointestinal stromal tumor (GIST) is the designation for the specific c-kit expressing and Kit-signaling driven mesenchymal tumors, many of which have Kit-activating mutations. The specific identification of GIST has become increasingly important because a Kit-selective tyrosine kinase inhibitor, imatinib (Glivec, formerly known as STI571, Novartis Pharma AG, Basel, Switzerland), has shown promise as an...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Communication
• Share to Cell Transformation, Neoplastic