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Article

Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells.

Molecular immunology - 1 Mar 2007

Tian Cuixia, Luskin Grace K, Dischert Kevin M, Higginbotham James N, Shepherd Bryan E, Crowe James E

Abstract excerpt

Memory B cells and the antibodies they encode are important for protective immunity against infectious pathogens. Characterization of naïve and memory B cell antibody repertoires will elucidate the molecular basis for the generation of antibody diversity in human B cells and the optimization of antibody structures that bind microbial antigens. In this study we aimed to investigate the influence of antigenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17196657
DOI: 10.1016/j.molimm.2006.11.020
PMCID: PMC1859862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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