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Article

Power to detect higher-order epistatic interactions in a metabolic pathway using a new mapping strategy.

Genetics - 1 May 2007

Stich Benjamin, Yu Jianming, Melchinger Albrecht E, Piepho Hans-Peter, Utz H Friedrich, Maurer Hans P, Buckler Edward S

Abstract excerpt

Epistatic interactions among quantitative trait loci (QTL) contribute substantially to the variation in complex traits. The main objectives of this study were to (i) compare three- vs. four-step genome scans to identify three-way epistatic interactions among QTL belonging to a metabolic pathway, (ii) investigate by computer simulations the power and proportion of false positives (PFP) for detecting three-way...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 17194777
DOI: 10.1534/genetics.106.067033
PMCID: PMC1893018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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