Article
DNA repair and mutant frequency in schizophrenia.
Mutation research - 1 Nov 1991
Magin G K, Robison S H, Breslin N, Wyatt R J, Alexander R C
Abstract excerpt
The in vivo frequency of mutants resulting from mutation at the hprt locus in human T-lymphocytes was determined with a cloning assay. T-lymphocytes were obtained from 14 individuals diagnosed with schizophrenia and 5 controls. No significant difference in mutant frequency was observed between the 2 groups. In addition, DNA-repair capacity was measured with the unscheduled DNA synthesis technique in lymphocytes...
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