Article
Multiregional Gene Expression Profiling Identifies MRPS6 as a Possible Candidate Gene for Parkinson's Disease
1 Mar 2006
Abstract excerpt
Combining large-scale gene expression approaches and bioinformatics may provide insights into the molecular variability of biological processes underlying neurodegeneration. To identify novel candidate genes and mechanisms, we conducted a multiregional gene expression analysis in postmortem brain. Gene arrays were performed utilizing Affymetrix HG U133 Plus 2.0 gene chips. Brain specimens from 21 different brain...
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