Article
Parkinson's disease candidate gene prioritization based on expression profile of midbrain dopaminergic neurons.
Journal of biomedical science - 17 Aug 2010
Vahedi Shahrooz, Rajabian Mehrnoosh, Misaghian Arman, Grbec Daniel, Simon Horst H, Alavian Kambiz N
Abstract excerpt
BACKGROUND: Parkinson's disease is the second most common neurodegenerative disorder. The pathological hallmark of the disease is degeneration of midbrain dopaminergic neurons. Genetic association studies have linked 13 human chromosomal loci to Parkinson's disease. Identification of gene(s), as part of the etiology of Parkinson's disease, within the large number of genes residing in these loci can be achieved...
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