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Article

Genetic association study on colony-stimulating factor 1 in Alzheimer's disease.

Neuro-degenerative diseases - 1 Jan 2006

Wollmer M Axel, Nitsch Roger M, Hock Christoph, Papassotiropoulos Andreas

Abstract excerpt

BACKGROUND: Colony-stimulating factor 1 (CSF1) regulates the proliferation and differentiation of myelomonocytic cells. Microglial cells of CSF1-deficient mice are reduced in number and are functionally impaired. CSF1-deficient mice exhibit subtle neurodevelopmental defects, enhanced neuronal vulnerability. Moreover, it has been reported that these mice may have amyloid-plaque-like depositions in the brain at an...

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Source

Identifiers

PMID: 17192722
DOI: 10.1159/000097302

Genes

CSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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