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Prevalence and Abundance of Latently Transcribed Varicella-Zoster Virus Genes in Human Ganglia

28 Dec 2006

Abstract excerpt

In human ganglia latently infected with varicella-zoster virus (VZV), sequence analysis has revealed that five viral genes (VZV genes 21, 29, 62, 63, and 66) are transcribed. However, their comparative prevalence and abundance are unknown. Here, using real-time PCR, we analyzed 28 trigeminal ganglia from 14 humans for RNA corresponding to the five virus genes known to be transcribed in latently infected human...

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PMID: 17192313
DOI: 10.1128/jvi.02745-06

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