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Varicella-Zoster Virus Gene 66 Transcription and Translation in Latently Infected Human Ganglia

27 May 2003

Abstract excerpt

Latent infection with varicella-zoster virus (VZV) is characterized by restricted virus gene expression and the absence of virus production. Of the approximately 70 predicted VZV genes, only five (genes 4, 21, 29, 62, and 63) have been shown by multiple techniques to be transcribed during latency. IE62, the protein product of VZV gene 62, is the major immediate-early (IE) virus-encoded transactivator of viral...

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PMID: 12767985
DOI: 10.1128/jvi.77.12.6660-6665.2003

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