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Varicella-Zoster Virus Gene Expression in Latently Infected and Explanted Human Ganglia

15 Dec 2000

Abstract excerpt

A consistent feature of varicella-zoster virus (VZV) latency is the restricted pattern of viral gene expression in human ganglionic tissues. To understand further the significance of this gene restriction, we used in situ hybridization (ISH) to detect the frequency of RNA expression for nine VZV genes in trigeminal ganglia (TG) from 35 human subjects, including 18 who were human immunodeficiency virus (HIV)...

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PMID: 11090189
DOI: 10.1128/jvi.74.24.11893-11898.2000

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