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Article

Multi-SNP pharmacogenomic classifier is superior to single-SNP models for predicting drug outcome in complex diseases.

Pharmacogenetics and genomics - 1 Feb 2009

Petrovski Slavé, Szoeke Cassandra E, Sheffield Leslie J, D'souza Wendyl, Huggins Richard M, O'brien Terence J

Abstract excerpt

OBJECTIVES: Most pharmacogenomic studies have attempted to identify single nucleotide polymorphism (SNP) markers that are predictive for treatment outcomes. It is, however, unlikely in complex diseases such as epilepsy, affecting heterogeneous populations, that a single SNP will adequately explain treatment outcomes. This study reports an approach to develop a multi-SNP model to classify treatment outcomes for...

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PMID: 19077679
DOI: 10.1097/FPC.0b013e32831d1dfa

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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