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Article

Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein.

Hepatology (Baltimore, Md.) - 1 Jan 2007

Visvanathan Kumar, Skinner Narelle A, Thompson Alex J V, Riordan Stephen M, Sozzi Vitini, Edwards Roslyn, Rodgers Sally, Kurtovic Jelica, Chang Judy, Lewin Sharon, Desmond Paul, Locarnini Stephen

Abstract excerpt

UNLABELLED: Toll-like receptors (TLRs) play a key role in the innate immune response. The aim of this study was to examine the expression of TLR2 and TLR4 in chronic hepatitis B (CHB). The TLR2 and TLR4 expression on hepatocytes and Kupffer cells from fresh liver biopsies was measured from 21 patients with untreated hepatitis B e antigen (HBeAg)-positive and HBeAg-negative CHB. Parallel studies were also...

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Share to Hepatocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Toll-Like Receptor 2

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Source

Identifiers

PMID: 17187404
DOI: 10.1002/hep.21482

Genes

TLR2
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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