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Article

Not interferon, but interleukin‐6 controls early gene expression in hepatitis B virus infection†‡

11 Aug 2009

Abstract excerpt

UNLABELLED: With about 350 million virus carriers, hepatitis B virus (HBV) infection remains a major health problem. HBV is a noncytopathic virus causing persistent infection, but it is still unknown whether host recognition of HBV may activate an innate immune response. We describe that upon infection of primary human liver cells, HBV is recognized by nonparenchymal cells of the liver, mainly by liver...

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PMID: 19937696
DOI: 10.1002/hep.23226

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