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Toll-like receptor polymorphisms are not associated with liver cirrhosis in hepatitis B virus infected Korean patients.

Hepato-gastroenterology - 1 Jan 2000

Kim Do Young, Choi Jong Won, Chang Hye Young, Kim Seung Up, Park Hana, Paik Yong Han, Kim Ja Kyung, Ahn Sang Hoon, Park Jun Yong, Chung Sook In, Lee Kwan Sik, Han Kwang Hyub, Chon Chae Yoon

Abstract excerpt

BACKGROUND/AIMS: Hepatitis B virus (HBV) induces inflammatory signaling leading to progressive liver damage. Polymorphisms of the toll-like receptor (TLR) 2 (Arg677Trp, Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes, which are important components of innate immunity against viral infection, have recently been described. We evaluated the association between TLR2 and TLR4 polymorphisms and the development of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21443084

Genes

TLR4
TLR2

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