Article
Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways.
World journal of gastroenterology - 7 Sept 2014
Pei Rong-Juan, Chen Xin-Wen, Lu Meng-Ji
Abstract excerpt
Hepatitis B virus (HBV) infection is one of the major causes of liver diseases, affecting more than 350 million people worldwide. The interferon (IFN)-mediated innate immune responses could restrict HBV replication at the different steps of viral life cycle. Indeed, IFN-α has been successfully used for treatment of patients with chronic hepatitis B. However, the role of the innate immune response in HBV...
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