Article
Repeated measurement sampling in genetic association analysis with genotyping errors.
Genetic epidemiology - 1 Feb 2007
Lai Renzhen, Zhang Hong, Yang Yaning
Abstract excerpt
Genotype misclassification occurs frequently in human genetic association studies. When cases and controls are subject to the same misclassification model, Pearson's chi-square test has the correct type I error but may lose power. Most current methods adjusting for genotyping errors assume that the misclassification model is known a priori or can be assessed by a gold standard instrument. But in practical...
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