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Article

Involvement of serotonin transporter gene polymorphisms (5-HTT) in impulsive behavior in the japanese population.

PloS one - 1 Jan 2015

Nomura Michio, Kaneko Masayuki, Okuma Yasunobu, Nomura Jun, Kusumi Ichiro, Koyama Tsukasa, Nomura Yasuyuki

Abstract excerpt

The serotonergic pathway has been implicated in the pathogenesis of impulsivity, and sensitivity to aversive outcomes may be linked to serotonin (5-HT) levels. Polymorphisms in the gene that encodes the serotonin transporter (5-HTT), which have differential effects on the level of serotonin transmission, display alternate responses to aversive stimuli. However, recent studies have shown that 5-HT does not affect...

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Identifiers

PMID: 25775400
DOI: 10.1371/journal.pone.0119743
PMCID: PMC4361639

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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