Article
Association between estrogen receptor alpha and beta gene polymorphisms and deep vein thrombosis.
Thrombosis research - 1 Jan 2007
Aléssio Aline Morandi, Höehr Nelci Fenalti, Siqueira Lúcia Helena, Ozelo Margareth Castro, de Pádua Mansur Antônio, Annichino-Bizzacchi Joyce Maria
Abstract excerpt
BACKGROUND: Estrogen and the estrogen receptors alpha (ESR1) and beta (ESR2) play a role in regulating genes, including coagulation and fibrinolysis genes. OBJECTIVE: We investigated the association between ESR1 c.454-397T>C and c.454-351A>G and ESR2 1082A>G and 1730A>G polymorphisms and the risk of deep vein thrombosis (DVT), in 134 patients and 134 controls with acquired risk factors for thrombosis associated...
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