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Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factor

1 Aug 1992

Abstract excerpt

Myxoma virus (MYX) is a leporipoxvirus of rabbits that induces a lethal syndrome characterized by disseminated tumorlike lesions, generalized immunosuppression, and secondary gram-negative bacterial infection. A MYX deletion mutant (vMYX-GF- delta M11L) was constructed to remove the entire myxoma growth factor (MGF) coding sequence and that for the C-terminal five amino acids of the partially overlapping upstream...

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PMID: 1629952
DOI: 10.1128/jvi.66.8.4720-4731.1992

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