Stable expression of the vaccinia virus K1L gene in rabbit cells complements the host range defect of a vaccinia virus mutant.

doi:10.1128/JVI.68.7.4109-4116.1994

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Article

Stable expression of the vaccinia virus K1L gene in rabbit cells complements the host range defect of a vaccinia virus mutant.

Journal of virology - 1 Jul 1994

Sutter G, Ramsey-Ewing A, Rosales R, Moss B

Abstract excerpt

Modified vaccinia virus Ankara (MVA), having acquired genomic deletions during passage in chicken embryo fibroblasts, is highly attenuated and unable to productively infect most mammalian cell lines. Multiplication in rabbit kidney-derived RK13 cells, but not other nonpermissive cells, can be res...

Topics

Animals
Base Sequence
Cells, Cultured
Chick Embryo
DNA Primers
Gene Expression Regulation, Viral
Genes, Viral
Genetic Complementation Test
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Rabbits
Simian virus 40
Transfection
Vaccinia virus
Viral Proteins
Virus Replication

Source

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Identifiers

PMID: 8207789
DOI: 10.1128/JVI.68.7.4109-4116.1994
PMCID: PMC236334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8207789-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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