Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ribosomal protein gene knockdown causes developmental defects in zebrafish.

PloS one - 20 Dec 2006

Uechi Tamayo, Nakajima Yukari, Nakao Akihiro, Torihara Hidetsugu, Chakraborty Anirban, Inoue Kunio, Kenmochi Naoya

Abstract excerpt

The ribosomal proteins (RPs) form the majority of cellular proteins and are mandatory for cellular growth. RP genes have been linked, either directly or indirectly, to various diseases in humans. Mutations in RP genes are also associated with tissue-specific phenotypes, suggesting a possible role in organ development during early embryogenesis. However, it is not yet known how mutations in a particular RP gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Brain
Share to Gene Targeting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis, Insertional

Share to Oligodeoxyribonucleotides, Antisense

Share to Ribosomal Proteins

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17183665
DOI: 10.1371/journal.pone.0000037
PMCID: PMC1762390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ribosomal protein gene knockdown causes developmental defects in zebrafish.PMID 17183665Read ↗

Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.Semantic proximity Read ↗

Many ribosomal protein genes are cancer genes in zebrafish.Semantic proximity Read ↗

Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.Semantic proximity Read ↗

Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system.Semantic proximity Read ↗

RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis.Semantic proximity Read ↗

Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.Semantic proximity Read ↗

A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.Semantic proximity Read ↗

Defects of protein production in erythroid cells revealed in a zebrafish Diamond-Blackfan anemia model for mutation in RPS19.Semantic proximity Read ↗

Nucleolin loss-of-function leads to aberrant FGF signaling and craniofacial anomaliesSemantic proximity Read ↗

The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome.Semantic proximity Read ↗

Silencing the Drosophila ribosomal protein L14 gene using targeted RNA interference causes distinct somatic anomalies.Semantic proximity Read ↗

Ribosome biogenesis protein Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.