Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.

doi:10.1371/journal.pgen.1003094

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Article

Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.

PLoS genetics - 1 Jan 2013

Watkins-Chow Dawn E, Cooke Joanna, Pidsley Ruth, Edwards Andrew, Slotkin Rebecca, Leeds Karen E, Mullen Raymond, Baxter Laura L, Campbell Thomas G, Salzer Marion C, Biondini Laura, Gibney Gretchen, Phan Dinh Tuy Françoise, Chelly Jamel, Morris H Douglas, Riegler Johannes, Lythgoe Mark F, Arkell Ruth M, Loreni Fabrizio, Flint Jonathan, Pavan William J, Keays David A

Abstract excerpt

The ribosome is an evolutionarily conserved organelle essential for cellular function. Ribosome construction requires assembly of approximately 80 different ribosomal proteins (RPs) and four different species of rRNA. As RPs co-assemble into one multi-subunit complex, mutation of the genes that encode RPs might be expected to give rise to phenocopies, in which the same phenotype is associated with...

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Identifiers

PMID: 23382688
DOI: 10.1371/journal.pgen.1003094
PMCID: PMC3561062

Genes

RPS7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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