Article
Isolation of Yersinia-specific T cell clones from the synovial membrane and synovial fluid of a patient with reactive arthritis.
Arthritis and rheumatism - 1 Sept 1991
Viner N J, Bailey L C, Life P F, Bacon P A, Gaston J S
Abstract excerpt
Synovial fluid (SF) mononuclear cells from patients with reactive arthritis (ReA) proliferate in vitro when challenged with ReA-associated bacteria, the maximal response being for the organism causing the triggering infection. We report the results of a study of the antigenic specificity of synovial T lymphocytes from an HLA-B27 positive ReA patient whose SF mononuclear cells responded preferentially to Yersinia...
Topics
- Adult
- Antibodies, Bacterial
- Arthritis, Infectious
- Arthritis, Reactive
- Biopsy, Needle
- Cell Separation
- Epitopes
- HLA-B27 Antigen
- Histocompatibility Antigens Class II
- Humans
- Male
