Article
Klebsiella pneumoniae-reactive T cells in blood and synovial fluid of patients with ankylosing spondylitis. Comparison with HLA-B27+ healthy control subjects in a limiting dilution study and determination of the specificity of synovial fluid T cell clones.
Arthritis and rheumatism - 1 Sept 1995
Hermann E, Sucké B, Droste U, Meyer zum Büschenfelde K H
Abstract excerpt
OBJECTIVE: To study the frequency of Klebsiella pneumoniae-responsive T cells in the peripheral blood (PB) of ankylosing spondylitis (AS) patients compared with that in healthy HLA-B27+ donors, and to examine T lymphocyte clones (TLC) derived from AS patient synovial fluid (SF) for the presence of Klebsiella reactivity. METHODS: Limiting dilution analysis of PB T cells in 8 patients with active AS and in 8...
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