Article
Functional analysis of synovial fluid and peripheral blood T cells from patients with rheumatoid arthritis.
Rheumatology international - 1 Jan 1995
van den Broek M, Boeije L, Swaak T, Smeenk R, Aarden L
Abstract excerpt
Rheumatoid arthritis is a T cell-mediated autoimmune disease. The lack of knowledge of the involved target antigens severely hampers research on relevant T cells in patients. Here we describe the functional analysis of freshly isolated T cells from the peripheral blood and the site of the lesion (synovial fluid or synovial membrane) of patients with rheumatoid arthritis. Healthy donors and osteoarthritis patients...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antigens, CD
- Arthritis, Rheumatoid
- CD4-Positive T-Lymphocytes
- Cell Division
- Female
- Humans
- Lymphokines
- Male
- Middle Aged